Diffuse axonal injury in mild traumatic brain injury: a 3D multivoxel proton MR spectroscopy study
نویسندگان
چکیده
منابع مشابه
Proton MR spectroscopy correlates diffuse axonal abnormalities with post-concussive symptoms in mild traumatic brain injury.
There are no established biomarkers for mild traumatic brain injury (mTBI), in part because post-concussive symptoms (PCS) are subjective and conventional imaging is typically unremarkable. To test whether diffuse axonal abnormalities quantified with three-dimensional (3D) proton magnetic resonance spectroscopic imaging (¹H-MRSI) correlated with patients' PCS, we retrospectively studied 26 mTBI...
متن کاملDiffuse metabolic abnormalities in acute mild traumatic brain injury: a quantitative proton MR spectroscopy study
INTRODUCTION: Traumatic brain injury (TBI) classified as ‘mild’ (mTBI) comprises 85% of cases, ~15% of which involve at least one nonresolving post-concussion syndrome symptom. It is not clear, however, whether the symptomatology is neurological and/or psychosomatic, since conventional imaging is usually unremarkable. Therefore, what distinguishes mild from more severe TBI is the lack of biomar...
متن کاملProton MR spectroscopy in mild traumatic brain injury
BACKGROUND To assess the role of 1H MRS in the detection of changes in cerebral metabolite levels in pyramidal tracts after mild traumatic brain injury (MTBI) and to compare metabolite alterations to the clinical status (Glasgow Coma Scale). MATERIAL/METHODS Study group consisted of 25 patients after mild traumatic brain injury, with a score of 11 to 15 in GCS. The MR studies were performed w...
متن کاملProton MR spectroscopic imaging depicts diffuse axonal injury in children with traumatic brain injury.
BACKGROUND AND PURPOSE Diffuse axonal injury (DAI) after traumatic brain injury (TBI) is important in patient assessment and prognosis, yet they are underestimated with conventional imaging techniques. We used MR spectroscopic imaging (MRSI) to detect DAI and determine whether metabolite ratios are accurate in predicting long-term outcomes and to examine regional differences in injury between c...
متن کاملDiffuse axonal injury in mild traumatic brain injury: a diffusion tensor imaging study.
OBJECT Diffuse axonal injury (DAI) is a major complication of traumatic brain injury (TBI) that leads to functional and psychological deficits. Although DAI is frequently underdiagnosed by conventional imaging modalities, it can be demonstrated using diffusion tensor imaging. The aim of this study was to assess the presence and extent of DAI in patients with mild TBI. METHODS Forty-six patien...
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ژورنال
عنوان ژورنال: Journal of Neurology
سال: 2012
ISSN: 0340-5354,1432-1459
DOI: 10.1007/s00415-012-6626-z